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Genome-wide gene–diet interaction analysis in the UK Biobank identifies novel effects on hemoglobin A1c

14 Apr 2021

Abstract excerpt

Diet is a significant modifiable risk factor for type 2 diabetes (T2D), and its effect on disease risk is under partial genetic control. Identification of specific gene-diet interactions (GDIs) influencing risk biomarkers such as glycated hemoglobin (HbA1c) is a critical step towards precision nutrition for T2D prevention, but progress has been slow due to limitations in sample size and accuracy of dietary...

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PMID: 33864366
DOI: 10.1093/hmg/ddab109

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