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Article

Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.

PLoS genetics - 1 Dec 2008

Paré Guillaume, Chasman Daniel I, Parker Alexander N, Nathan David M, Miletich Joseph P, Zee Robert Y, Ridker Paul M

Abstract excerpt

Type 2 diabetes is a leading cause of morbidity and mortality. While genetic variants have been found to influence the risk of type 2 diabetes mellitus, relatively few studies have focused on genes associated with glycated hemoglobin, an index of the mean blood glucose concentration of the preceding 8-12 weeks. Epidemiologic studies and randomized clinical trials have documented the relationship between glycated...

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Identifiers

PMID: 19096518
DOI: 10.1371/journal.pgen.1000312
PMCID: PMC2596965

Genes

GCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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