Article

Rational Selection of PCR Primer/Probe Design Sites for SARS-CoV-2

2021-04-05

Abstract excerpt

Various reports of decreased analytical sensitivities of real-time PCR-based detection of Coronavirus Disease 2019 (COVID-19) have been associated with occurrence of mutations in the target area of primer/probe binding. Knowledge about propensities of different genes to undergo mutation can inform researchers to select optimal genes to target for the qPCR design. We analyzed supplementary data from over 45 thousan...

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Literature Corpus work: 5127569e-2246-5c40-90bf-03c5ea8d1c8b
DOI: 10.1101/2021.04.04.438420

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