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Cell-type specific regulation of human interstitial collagenase-1 gene expression by interleukin-1β (IL-1β) in human fibroblasts and BC-8701 breast cancer cells

1997-09-01

Abstract excerpt

Interleukin-1β (IL-1β) is a potent cytokine that stimulates interstitial collagenase-1 (matrix metalloproteinase-1; MMP-1). In this study, we compared the mechanism(s) by which IL-1β induces collagenase gene expression in two very different cells, normal human foreskin fibroblasts (HFFs) and an aggressive breast cancer cell line, BC-8701 cells. Northern analysis showed that the time course of collagenase induction...

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Literature Corpus work
51186d22-42a5-568a-b845-873ff52d4821
DOI
10.1002/(sici)1097-4644(19970901)66:3<322::aid-jcb5>3.0.co;2-r
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Cell-type specific regulation of human interstitial collagenase-1 gene expression by interleukin-1β (IL-1β) in human fibroblasts and BC-8701 breast cancer cellsDOI 10.1002/(sici)1097-4644(19970901)66:3<322::aid-jcb5>3.0.co;2-r
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