Article

Gene and cell therapy strategies for the treatment of cardiac hypertrophy : understanding the role of insulin-like growth factor-1

2014-01-01

Abstract excerpt

Cardiac hypertrophy is a growth response elicited in the heart by intrinsic and extrinsic stimuli in pathological as well as physiological conditions. The insulin-like growth factor-1 (IGF-1) propeptides regulate cardiac hypertrophy during normal development, although their role during pathological hypertrophy has yet to be explored. Previous data from our laboratory has shown that the locally acting propeptide IG...

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Literature Corpus work: 50c91123-27bb-5427-bf61-e1576bb94544
DOI: 10.25560/24547

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