Article

Divergent iron-regulatory states contribute to heterogeneity in breast cancer aggressiveness

2023-06-26

Abstract excerpt

Primary tumors with similar mutational profiles can progress to vastly different outcomes where transcriptional state, rather than mutational profile, predicts prognosis. A key challenge is to understand how distinct tumor cell states are induced and maintained. In triple negative breast cancer cells, invasive behaviors and aggressive transcriptional signatures linked to poor patient prognosis can emerge in respon...

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Literature Corpus work: 50c83607-6602-5b89-8994-6b5450bcc039
DOI: 10.1101/2023.06.23.546216

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