Article

Dapagliflozin attenuates LPS-induced myocardial injury by reducing ferroptosis

2024-02-22

Abstract excerpt

<title>Abstract</title> <p>Lipopolysaccharide induces sepsis in vivo, with a significant proportion of septic patients progressing to septic cardiomyopathy. Previous studies have reported the involvement of ferroptosis in the pathogenesis of septic cardiomyopathy. SGLT2 inhibitors such as dapagliflozin have been demonstrated to have cardioprotective effects, with reports indicating a reduction in myocardial ische...

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Literature Corpus work: 509c41a6-0c55-50aa-8537-bbea8e520830
DOI: 10.21203/rs.3.rs-3958232/v1

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