Back to search

Article

Down-regulation of HSPB1 and MGST1 promote ferroptosis and impact immune infiltration in diabetic cardiomyopathy

2024-12-09

Abstract excerpt

<title>Abstract</title> <p>Diabetic cardiomyopathy (DCM) is a leading cause of death in diabetic patients. Current therapies do not adequately resolve this problem and focus only on the optimal level of blood glucose for patients. Ferroptosis plays an important role in diabetes mellitus and cardiovascular diseases. However, the role of ferroptosis in DCM remains unclear. Differentially expressed ferroptosis-relat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b930afa8-d160-5ee7-a732-bdc46387e8d9
DOI
10.21203/rs.3.rs-5153598/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Down-regulation of HSPB1 and MGST1 promote ferroptosis and impact immune infiltration in diabetic cardiomyopathyDOI 10.21203/rs.3.rs-5153598/v1
Genetic analysis of potential biomarkers and therapeutic targets in ferroptosis from coronary artery diseaseSemantic proximity
The stress-responsive protein REDD1 drives diabetic myocardial injury via activation of autophagy-dependent ferroptosisSemantic proximity
From bench to bedside: targeting ferroptosis and mitochondrial damage in the treatment of diabetic cardiomyopathySemantic proximity
Analysis of differentially expressed genes related to the development of diabetic cardiomyopathy in the myocardium of type-2 diabetic ratsSemantic proximity
Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysisSemantic proximity
Identifying the Oxidative Stress-Related Diagnostic Biomarkers in Dilated Cardiomyopathy by Bioinformatics AnalysisSemantic proximity
Identification of important modules and biomarkers in diabetic cardiomyopathy based on WGCNA and LASSO analysisSemantic proximity
Single‐cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia–reperfusion injurySemantic proximity
Consensus Clustering Analysis Identifies Ferroptosis-Related Patient Clusters and Predictive Signature Construction Based on Ferroptosis-Related Genes in Ischemic CardiomyopathySemantic proximity
Exploring the molecular biology of ischemic cardiomyopathy based on ferroptosis‑related genesSemantic proximity
Diagnostic and predictive values of ferroptosis-related genes in heart failureSemantic proximity
Identification of Novel Targets for Treatment of Dilated Cardiomyopathy Based on the Ferroptosis and Immune HeterogeneitySemantic proximity
Select a neighboring publication to make it the new centre.