Article

Smooth muscle expression of RNA editing enzyme <i>ADAR1</i> controls activation of RNA sensor MDA5 in atherosclerosis

2024-07-11

Abstract excerpt

Mapping the genomic architecture of complex disease has been predicated on the understanding that genetic variants influence disease risk through modifying gene expression. However, recent discoveries have revealed that a significant burden of disease heritability in common autoinflammatory disorders and coronary artery disease (CAD) is mediated through genetic variation modifying post-transcriptional modification...

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Literature Corpus work: 507483d7-1008-59aa-a549-31e8f950465a
DOI: 10.1101/2024.07.08.602569

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