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Identification of a novel immune-related gene signature by single-cell and bulk sequencing for the prediction of the immune landscape and prognosis of breast cancer

3 Dec 2024

Abstract excerpt

BACKGROUND: As a common cause of cancer-related deaths in women, BRCA (breast cancer) shows complexity and requires precise biomarkers and treatment methods. This study delves into the molecular makeup of BRCA, focusing on immune profiles, molecular subtypes, gene expression and single-cell analysis. METHODS: XCell was used to assess immune infiltration based on TCGA (the Cancer Genome Atlas) data and the...

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Cancer Genomics and Diagnostics
Cancer Immunotherapy and Biomarkers
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39627792
DOI: 10.1186/s12935-024-03589-7

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