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Integrative Single-Cell Transcriptomics and Co-Expression Network Analysis Identify SIMALR as a Prognostic Immune-Related LncRNA in Breast Cancer: In Silico Analysis and Validation

2025-10-15

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<title>Abstract</title> <p> <bold>Purpose</bold> This study aimed to identify and characterize irLncRNAs associated with prognosis and immune modulation in breast cancer. <bold>Methods</bold> We integrated single-cell RNA sequencing hdWGCNA and bulk RNA-seq differential expression analysis results to identify candidate irLncRNAs. The top candidate, SIMALR, was further investigated using immune, survival, muta...

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Literature Corpus work
c093bb02-1778-545e-9a10-8d9c152be657
DOI
10.21203/rs.3.rs-7739331/v1
Open publication

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Integrative Single-Cell Transcriptomics and Co-Expression Network Analysis Identify SIMALR as a Prognostic Immune-Related LncRNA in Breast Cancer: In Silico Analysis and ValidationDOI 10.21203/rs.3.rs-7739331/v1
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