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Structural determination of <i>Rickettsia</i> lipid A without chemical extraction confirms shorter acyl chains in later-evolving Spotted Fever Group pathogens

2023-07-06

Abstract excerpt

<h4>ABSTRACT</h4> Rickettsiae are Gram-negative obligate intracellular parasites of numerous eukaryotes. Human pathogens of the Transitional Group (TRG), Typhus Group (TG), and Spotted Fever Group (SFG) rickettsiae infect blood-feeding arthropods, have dissimilar clinical manifestations, and possess unique genomic and morphological attributes. Lacking glycolysis, rickettsiae pilfer numerous metabolites from host...

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Literature Corpus work
4fa43caf-773a-57a9-a496-21dc4d22ca3c
DOI
10.1101/2023.07.06.547954
Open publication

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Structural determination of <i>Rickettsia</i> lipid A without chemical extraction confirms shorter acyl chains in later-evolving Spotted Fever Group pathogensDOI 10.1101/2023.07.06.547954
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