Article
Profound Opioid and Medetomidine Withdrawal: A Case Series and Narrative Review of Available Literature
2025-10-22
Abstract excerpt
Medetomidine, a potent central acting α2 agonist, has emerged as a fentanyl adulterant in the non-medical opioid supply. Its use has been linked to a novel withdrawal syndrome that is often resistant to conventional treatment protocols. Four cases are presented exemplifying extreme, but increasingly common forms of this withdrawal syndrome. A literature review is provided demonstrating both the paucity of availabl...
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Identifiers and source
- Literature Corpus work
- 4f213c9f-7f15-5583-9962-bb12706b79e9
- DOI
- 10.20944/preprints202508.0751.v4