Article

RDH10 and ATRA sensitize triple-negative breast cancer to taxane-based chemotherapy through regulation of PIN1

2021-01-27

Abstract excerpt

<h4>Background: </h4> With few targeted therapies available for triple-negative breast cancer (TNBC), there is a critical need to identify biomarkers that can predict chemotherapy-response. Copy number amplifications (CNAmps) have been implicated in tumorigenesis, progression, and treatment response. Previously, we performed a prospective neoadjuvant chemotherapy study (BEAUTY) and identified a 5 Mb CNAmp in TNBC...

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Literature Corpus work: 4ef81152-cecd-5e10-adeb-7ce3059353b7
DOI: 10.21203/rs.3.rs-86064/v2

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