Article

Metax: A Coverage-Informed Probabilistic Framework for Accurate Cross-Domain Taxon Profiling

2025-12-06

Abstract excerpt

Metagenomic taxonomic profiling is essential for characterizing microbial community composition in both environmental and clinical contexts. Existing profilers have greatly advanced community characterization; however, achieving accurate profiling across all domains of life - especially for archaea, fungi, and viruses - and for low-biomass, host-dominated samples, remains challenging. We describe Metax, a cross-do...

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Literature Corpus work: 4e843ff2-9943-5152-96cb-9553f565d7a9
DOI: 10.64898/2025.12.04.692287

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