Article
Comprehensive Cross-Domain Taxonomic Classification of Microbiotas using Partitioned Amplification Multiplexed Amplicon Sequencing (PAMA-seq)
2025-06-19
Abstract excerpt
Microbial communities encompass diverse bacteria, archaea, and eukaryotes that play vital roles in ecosystems and host health. Comprehensive analysis of these communities requires accurate, quantitative, and cross-domain profiling, yet current sequencing methods—metagenome shotgun sequencing (MGS) and ribosomal RNA (rRNA) amplicon sequencing—struggle to achieve these goals in a single assay. MGS provides broad fun...
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Identifiers and source
- Literature Corpus work
- 19bdf30d-16d2-5826-b338-fb8c85b80fb9
- DOI
- 10.1101/2025.06.18.660470
