Article

Profiling Systemic IgG-Targeted Gut Microbiota Reveals Disease Activity–Associated Bacterial Signatures in Ulcerative Colitis

2026-08-12

Abstract excerpt

Aberrant systemic IgG responses to the gut microbiota may be implicated in the pathogenesis of ulcerative colitis (UC). In this study, we investigated IgG-targeted bacteria and their predicted functional characteristics in UC. Using fecal samples and autologous sera from 37 patients with UC and 4 healthy controls, we profiled IgG-targeted bacteria under in vitro conditions using 16S rRNA gene sequencing. To correc...

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Literature Corpus work: 4e67b0b9-aceb-529a-b008-5dde063f66ea
DOI: 10.20944/preprints202608.0841.v1

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