Back to search

Article

Pediatric CML progression to Blast crisis: A Case report and review

2024-09-11

Abstract excerpt

<h4>Background: </h4> Chronic Myeloid Leukemia (CML) is a rare malignancy among children, having an incidence of 1 in a million. It is driven by the Philadelphia chromosome, resulting in the BCR-ABL1 fusion gene. Pediatric cases typically present in the chronic phase and are managed with tyrosine kinase inhibitors (TKIs) like imatinib. However, some cases progress to blast crisis, leading to life-threatening compl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4e546447-8b60-5d9b-b2d8-90fc16043430
DOI
10.22541/au.172604891.18305961/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Pediatric CML progression to Blast crisis: A Case report and reviewDOI 10.22541/au.172604891.18305961/v1
Chronic Myeloid Leukemia, from Pathophysiology to Treatment-Free Remission: A Narrative Literature ReviewSemantic proximity
Chronic myeloid leukemia: cytogenetics and molecular biology’s part in the comprehension and management of the pathology and treatment evolutionSemantic proximity
How I treat the blast phase of Philadelphia chromosome–negative myeloproliferative neoplasmsSemantic proximity
Pathobiology of lymphoid and myeloid blast crisis and management issues.Semantic proximity
Chronic Myelogenous Leukemia,BCR-ABL1+Semantic proximity
Chronic Myeloid Leukemia in 2007Semantic proximity
Molecular and cellular bases of chronic myeloid leukemiaSemantic proximity
Allogeneic Hematopoietic Stem Cell Transplantation in Infant Leukemia: Vague Prospects? (Series Cases and Brief Review)Semantic proximity
A Case Report of Chronic Myelogenous Leukemia Presenting as Blastic Crisis with a T-Cell Acute Lymphoblastic Leukemia Phenotype: Awareness of a Rare Entity.Semantic proximity
The Biology of CML blast crisis.Semantic proximity
Clinical course of juvenile myelomonocytic leukemia in the blast crisis phase treated by acute myeloid leukemia-oriented chemotherapy and allogeneic hematopoietic stem cell transplantation.Semantic proximity
Chronic myeloid leukemia presenting in lymphoblastic crisis, a differential diagnosis with Philadelphia-positive B-lymphoblastic leukemiaSemantic proximity
Select a neighboring publication to make it the new centre.