Article

Sirt3 Regulates Radioresistance of Non-small Cell Lung Cancer through ATM-Chk2 Pathway

2020-04-08

Abstract excerpt

<title>Abstract</title> <p>With high incidence and mortality, non-small cell lung cancer (NSCLC) represent 85-90% in all lung cancer patients. In addition to surgery and chemotherapy, radiotherapy is an indispensable approach for cancer treatment. However, cellular resistance to ionizing radiation often results in failure in treatment. In this study, we aimed to investigate the role of Sirt3 in radiotherapy on NS...

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Literature Corpus work: 4e2f9de6-c457-5687-89df-a22ed5371ada
DOI: 10.21203/rs.3.rs-20854/v1

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