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Article

Alterations of host-gut microbiome interactions in multiple sclerosis

27 Jan 2022

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) has a complex genetic, immune and metabolic pathophysiology. Recent studies implicated the gut microbiome in MS pathogenesis. However, interactions between the microbiome and host immune system, metabolism and diet have not been studied over time in this disorder. METHODS: We performed a six-month longitudinal multi-omics study of 49 participants (24 untreated relapse remitting...

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PMID: 35094961
DOI: 10.1016/j.ebiom.2021.103798

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