Article

Non-intuitive trends of fetal fraction development related to gestational age and fetal gender, and their practical implications for non-invasive prenatal testing

2022-04-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Discovery of fetal cell-free DNA fragments in maternal blood revolutionized prenatal diagnostics. Although non-invasive prenatal testing (NIPT) is already a matured screening test with high specificity and sensitivity, the accurate estimation of the proportion of fetal fragments, called fetal fraction, is crucial to avoid false-negative results. <h4>Methods</h4> We collected 69...

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Literature Corpus work: 4d68caae-5f90-5fb4-ba92-8abaf85442a8
DOI: 10.1101/2022.04.07.22273556

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