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Factors Affecting the Fetal Fraction in Noninvasive Prenatal Screening: A Review

27 Jan 2022

Abstract excerpt

A paradigm shift in noninvasive prenatal screening has been made with the discovery of cell-free fetal DNA in maternal plasma. Noninvasive prenatal screening is primarily used to screen for fetal aneuploidies, and has been used globally. Fetal fraction, an important parameter in the analysis of noninvasive prenatal screening results, is the proportion of fetal cell-free DNA present in the total maternal plasma...

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PMID: 35155308
DOI: 10.3389/fped.2022.812781

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