Article

Virtue as the mean: Pan-human consensus genome significantly improves the accuracy of RNA-seq analyses

2020-12-22

Abstract excerpt

The Human Reference Genome serves as the foundation for modern genomic analyses. However, in its present form, it does not adequately represent the vast genetic diversity of the human population. In this study, we explored the consensus genome as a potential successor of the current Reference genome and assessed its effect on the accuracy of RNA-seq read alignment. In order to find the best haploid genome represen...

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Literature Corpus work: 4ce7dd3a-d487-597f-9570-e9c97ec1dc99
DOI: 10.1101/2020.12.22.423111

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