Article
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly
2016-08-29
Abstract excerpt
The human reference genome assembly plays a central role in nearly all aspects of today’s basic and clinical research. GRCh38 is the first coordinate-changing assembly update since 2009 and reflects the resolution of roughly 1000 issues and encompasses modifications ranging from thousands of single base changes to megabase-scale path reorganizations, gap closures and localization of previously orphaned sequences....
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Identifiers and source
- Literature Corpus work
- 0d14156c-792b-5662-92d6-caa4ec9fbbef
- DOI
- 10.1101/072116