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HPRC2: A human pangenome reference with near-complete coverage of common genetic variation

2026-07-22

Abstract excerpt

A pangenome reference overcomes the inherent limitation of any individual reference genome by integrating the variation present in a population. We present the Human Pangenome Reference Consortium's (HPRC) Release 2 (HPRC2), an openly available, second phase pangenome that is an approximately fivefold expansion in genome number over HPRC Release 1 (HPRC1) and measurable improvement in genome completeness, contigui...

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Literature Corpus work
5949c3d6-d362-5359-a3f4-f1ec009f80c0
DOI
10.64898/2026.07.21.739710
Open publication

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HPRC2: A human pangenome reference with near-complete coverage of common genetic variationDOI 10.64898/2026.07.21.739710
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