Article
The diploid genome sequence of an individual human.
PLoS biology - 4 Sept 2007
Levy Samuel, Sutton Granger, Ng Pauline C, Feuk Lars, Halpern Aaron L, Walenz Brian P, Axelrod Nelson, Huang Jiaqi, Kirkness Ewen F, Denisov Gennady, Lin Yuan, MacDonald Jeffrey R, Pang Andy Wing Chun, Shago Mary, Stockwell Timothy B, Tsiamouri Alexia, Bafna Vineet, Bansal Vikas, Kravitz Saul A, Busam Dana A, Beeson Karen Y, McIntosh Tina C, Remington Karin A, Abril Josep F, Gill John, Borman Jon, Rogers Yu-Hui, Frazier Marvin E, Scherer Stephen W, Strausberg Robert L, Venter J Craig
Abstract excerpt
Presented here is a genome sequence of an individual human. It was produced from approximately 32 million random DNA fragments, sequenced by Sanger dideoxy technology and assembled into 4,528 scaffolds, comprising 2,810 million bases (Mb) of contiguous sequence with approximately 7.5-fold coverage for any given region. We developed a modified version of the Celera assembler to facilitate the identification and...
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