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Validation of human telomere length trans-ancestry meta-analysis association signals identifies <i>POP5</i> and <i>KBTBD6</i> as novel human telomere length regulation genes

2023-07-14

Abstract excerpt

Telomere length genome-wide association studies (GWAS) have become well-powered to detect novel genes in telomere length regulation. However, no prior work has validated these putative novel genes to confirm the contribution of GWAS loci to telomere length regulation. We conducted a trans-ancestry meta-analysis of 211,369 individuals. Through enrichment analyses of chromatin state and cell-type heritability we ide...

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Literature Corpus work
4c9d3db3-3d0f-5471-9e26-bc575e764056
DOI
10.1101/2023.07.12.548702
Open publication

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Validation of human telomere length trans-ancestry meta-analysis association signals identifies <i>POP5</i> and <i>KBTBD6</i> as novel human telomere length regulation genesDOI 10.1101/2023.07.12.548702
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