Article

Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed

2019-09-04

Abstract excerpt

<h4>ABSTRACT</h4> Telomeres shorten in replicating somatic cells, and telomere length (TL) is associated with age-related diseases 1,2 . To date, 17 genome-wide association studies (GWAS) have identified 25 loci for leukocyte TL 3–19 , but were limited to European and Asian ancestry individuals and relied on laboratory assays of TL. In this study from the NHLBI Trans-Omics for Precision Medicine (TOPMed) progra...

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Literature Corpus work: 45ce0319-59d6-582b-ac18-9560f70c173a
DOI: 10.1101/749010

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