Article

A framework for translation of genomic responses from mouse models to human inflammatory disease contexts

2018-06-13

Abstract excerpt

<h4>ABSTRACT</h4> The high failure rate of therapeutics showing promise in mouse disease models to translate to patients is a pressing challenge in biomedical science. However, mouse models are a useful tool for evaluating mechanisms of disease and prioritizing novel therapeutic agents for clinical trials. Though retrospective studies have examined the fidelity of mouse models of inflammatory disease to their res...

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Identifiers and source

Literature Corpus work: 3f28f294-c515-582d-945d-9975c90a91d9
DOI: 10.1101/346122

Open publication

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