Article

Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells

2020-09-11

Abstract excerpt

<h4>ABSTRACT</h4> Cystic fibrosis (CF) is a genetic disease characterized by CF transmembrane regulator (CFTR) dysfunction. With over 2000 CFTR variants identified, in addition to known patient to patient variability, there is a need for personalized treatment. The discovery of CFTR modulators has shown efficacy in certain CF populations, however there are still CF populations without valid therapeutic options. W...

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Literature Corpus work: 4be09044-5b47-5793-a782-09153dfbd8c8
DOI: 10.1101/2020.09.11.294223

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