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Integrated proteomics and metabolomics analysis reveals new insight into the synergistic antitumor effect of valproic acid plus simvastatin in prostate cancer xenograft model associated with downmodulation of YAP/TAZ signaling

2024-03-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Despite advancements in therapeutic approaches, including taxane-based chemotherapy and androgen receptor targeting agents, metastatic castration-resistant prostate cancer (mCRPC) remains an incurable tumour, underlying the need of novel strategies that can target the complexities of this disease and bypass the development of drug-resistance mechanisms. We previ...

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Literature Corpus work
4bd66e9d-9664-5a70-82a9-bdfda0a82c93
DOI
10.21203/rs.3.rs-4086640/v1
Open publication

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Integrated proteomics and metabolomics analysis reveals new insight into the synergistic antitumor effect of valproic acid plus simvastatin in prostate cancer xenograft model associated with downmodulation of YAP/TAZ signalingDOI 10.21203/rs.3.rs-4086640/v1
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