Article

Analysis-ready VCF at Biobank scale using Zarr

2024-06-12

Abstract excerpt

<h4>Background</h4> Variant Call Format (VCF) is the standard file format for interchanging genetic variation data and associated quality control metrics. The usual row-wise encoding of the VCF data model (either as text or packed binary) emphasises efficient retrieval of all data for a given variant, but accessing data on a field or sample basis is inefficient. Biobank scale datasets currently available consist...

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Literature Corpus work: 4bb2256f-156a-5e40-83f4-3b3f729b4714
DOI: 10.1101/2024.06.11.598241

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