Article
A spectrum of free software tools for processing the VCF variant call format: vcflib, bio-vcf, cyvcf2, hts-nim and slivar.
PLoS computational biology - 1 May 2022
Garrison Erik, Kronenberg Zev N, Dawson Eric T, Pedersen Brent S, Prins Pjotr
Abstract excerpt
Since its introduction in 2011 the variant call format (VCF) has been widely adopted for processing DNA and RNA variants in practically all population studies-as well as in somatic and germline mutation studies. The VCF format can represent single nucleotide variants, multi-nucleotide variants, insertions and deletions, and simple structural variants called and anchored against a reference genome. Here we present...
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