Article

Sparse Project VCF: efficient encoding of population genotype matrices

2019-04-17

Abstract excerpt

<h4>Summary</h4> Variant Call Format (VCF), the prevailing representation for germline genotypes in population sequencing, suffers rapid size growth as larger cohorts are sequenced and more rare variants are discovered. We present Sparse Project VCF (spVCF), an evolution of VCF with judicious entropy reduction and run-length encoding, delivering >10X size reduction for modern studies with practically minimal info...

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Literature Corpus work: 495a0f22-98a9-55e8-86a6-915c7b03e9be
DOI: 10.1101/611954

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