Article

Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis

2024-09-25

Abstract excerpt

<h4>Introduction</h4> Environmental exposure to dioxin has been linked to increased myocardial infarction. Smooth muscle cells (SMC) in the coronary vasculature play a critical role in atherosclerotic plaque remodeling due to their phenotypic plasticity, however, the detailed mechanism linking dioxin exposure to adverse SMC modulation is not well understood. <h4>Methods</h4> Single-cell RNA and ATAC sequencing a...

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Literature Corpus work: 4b51e6c2-eb0a-508c-bdcb-bd52c3df3416
DOI: 10.1101/2024.09.24.614572

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