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Erythropoietin reshapes the adult hippocampal chromatin landscape to promote neurogenesis

2025-10-14

Abstract excerpt

<h4>ABSTRACT</h4> Understanding the molecular mechanisms by which erythropoietin (EPO) acts as neurotrophic factor that enhances hippocampal function and learning is essential to harness its therapeutic potential. Here, we employ single-nucleus ATAC-seq and RNA-seq to map the epigenomic and transcriptional landscapes of adult mouse hippocampus under recombinant human EPO (rhEPO) treatment. We discover significant...

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Literature Corpus work
4b3a88f6-6283-5307-b26c-74aec050aa0e
DOI
10.1101/2025.10.13.682070
Open publication

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Erythropoietin reshapes the adult hippocampal chromatin landscape to promote neurogenesisDOI 10.1101/2025.10.13.682070
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