Article

Semaphorin-4D Signaling in Recruiting Dental Stem Cells for Vascular Stabilization

2024-11-29

Abstract excerpt

<title>Abstract</title> <p>Background Achieving a stable vasculature is crucial for tissue regeneration. Endothelial cells initiate vascular morphogenesis, followed by mural cells that stabilize new vessels. This study investigates the in vivo effects of Sema4D-Plexin-B1 signaling on stem cells from human exfoliated deciduous teeth (SHED)-supported angiogenesis, focusing on its mechanism in PDGF-BB secretion. We...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4b2f4ff5-a366-52f6-9456-b71e98489b8a
DOI: 10.21203/rs.3.rs-5321597/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Semaphorin-4D Signaling in Recruiting Dental Stem Cells for Vascular StabilizationDOI 10.21203/rs.3.rs-5321597/v1Read

EHD1 Modulation in Hypoxic Preconditioning of SHED Enhances Angiogenesis: A Preliminary ResearchSemantic proximity Read

Dentin matrix protein 1 and HUVEC-ECM scaffold promote the differentiation of human dental pulp stem cells into endothelial lineage: implications in regenerative medicineSemantic proximity Read

Vascular and Lymphatic Dysregulation via Non-EndoMT <i>Col2a1</i> Signaling in Bisphosphonate-Related Osteonecrosis of the JawSemantic proximity Read

Single-cell transcriptomics identifies PDGFRA+ progenitors orchestrating angiogenesis and periodontal tissue regenerationSemantic proximity Read

Single-cell RNA sequencing reveals vascularization-associated cell subpopulations in dental pulp: PDGFRβ+ DPSCs with activated PI3K/AKT pathwaySemantic proximity Read

Effect of CD146 on Bone Regeneration by Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth into Mouse Skull DefectSemantic proximity Read

Class-3 semaphorins: Potent multifunctional modulators for angiogenesis-associated diseasesSemantic proximity Read

Next-Gen Dental Therapies: Bridging Bioengineering with Pharmacological ScienceSemantic proximity Read

Analysis of tumor stem cell recruitment and integration in microvascular architectural heterogeneity during oral mucosal carcinogenesis: an in vivo experimental study.Semantic proximity Read

Human Bone Marrow Mesenchymal Stem Cell-derived Extracellular Vesicles Restore Th17/Treg Homeostasis in Periodontitis via miR-1246Semantic proximity Read

CD105 is regulated by hsa-miR-1287 and its expression is inversely correlated with osteopotential in SHEDSemantic proximity Read

ID3 contributes to the acquisition of molecular stem cell-like signature in microvascular endothelial cells: its implication for understanding microvascular diseases.Semantic proximity Read