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Human Bone Marrow Mesenchymal Stem Cell-derived Extracellular Vesicles Restore Th17/Treg Homeostasis in Periodontitis via miR-1246

2023-03-30

Abstract excerpt

<title>Abstract</title> <p> T-cell-mediated immunity is crucial in the immunopathology of periodontitis. The restoration of the equilibrium between the T helper cell 17 (Th17) and regulatory T cell (Treg) subsetsby extrcellular vesicles (EVs) obtained from human bone marrow stem cells (hBMSCs) promotes new bone formation and suppresses inflammation. Uncovering the functions of hBMSC-derived EVs in the immune mic...

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Literature Corpus work
17e795cd-c67c-500d-a50d-a37f38a2ad34
DOI
10.21203/rs.3.rs-1961434/v2
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