Article

GPS-Net: discovering prognostic pathway modules based on network regularized kernel learning

2024-07-18

Abstract excerpt

The search for prognostic biomarkers capable of predicting patient outcomes, by analyzing gene expression in tissue samples and other molecular profiles, remains largely on single-gene-based or global-gene-search approaches. Gene-centric approaches, while foundational, fail to capture the higher-order dependencies that reflect the activities of co-regulated processes, pathway alterations, and regulatory networks,...

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Literature Corpus work: 4b1b2807-aa95-5962-afae-852133d2c057
DOI: 10.1101/2024.07.15.603645

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