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Article

<i>In vitro</i> gut modeling as a tool for adaptive evolutionary engineering of <i>Lactiplantibacillus plantarum</i>

2020-10-23

Abstract excerpt

Research and marketing of probiotics demand for holistic strain improvement considering both, the biotic and abiotic gut environment. Here we aim to establish the continuous In vitro colonic fermentation model PolyFermS as a tool for adaptive evolutionary engineering. Immobilized fecal microbiota from adult donors were steadily cultivated up to 72 days in PolyFermS reactors, providing a long-term compositional an...

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Identifiers and source

Literature Corpus work
4b1782c0-098b-5667-8d0b-3ee32f640187
DOI
10.1101/2020.10.21.349795
Open publication

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