Back to search

Article

Pangenome-based design of strain-specific primers enables precise monitoring of bacteria in human microbiome intervention trials

2025-12-19

Abstract excerpt

<title>Abstract</title> <p> Lactic acid bacteria (LAB), including many well-known beneficial bacteria, are increasingly used in diverse applications, including probiotics. Among these, strains of Lactobacillaceae are extensively researched. Monitoring the survival and persistence of specific strains in across niches remains a challenge, as selective techniques at strain level are often lacking. Here, we present...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f9322ce1-9673-52bf-8f73-096a2133e60e
DOI
10.21203/rs.3.rs-8210879/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Pangenome-based design of strain-specific primers enables precise monitoring of bacteria in human microbiome intervention trialsDOI 10.21203/rs.3.rs-8210879/v1
Pangenome-based design of strain-specific primers allows the specific monitoring of engraftment in different habitatsSemantic proximity
Development and application of a SNP-based strain-specific identification PCR method for Bifidobacterium animalis subsp. lactis BL-99 using PCR coupled with sanger sequencing.Semantic proximity
Highly accurate and sensitive absolute quantification of bacterial strains in human fecal samplesSemantic proximity
The curated Lactobacillus acidophilus NCFM genome provides insights into strain specificity and microevolution.Semantic proximity
Comprehensive Complete-Genome Analysis of <i>Lactobacillaceae</i> and <i>Bifidobacteriaceae</i> Reveals Strain-Specific Metabolic Interactions in Chinese Gut MicrobiotaSemantic proximity
Genomic characterization of Lactobacillus fermentum DSM 20052.Semantic proximity
Evaluation of an effective detection and quantification method for particular microorganisms by comparing NGS-based metagenome profiling dataSemantic proximity
Characterization of Resistome in Lactobacillus Genomic Sequences From the Human GutSemantic proximity
The Genomic Basis of Lactobacilli as Health-Promoting Organisms.Semantic proximity
Diversity, vitality and activities of intestinal lactic acid bacteria and bifidobacteria assessed by molecular approaches.Semantic proximity
Development of a single nucleotide polymorphism-based strain-identified method for Streptococcus thermophilus CICC 6038 and Lactobacillus delbrueckii ssp. bulgaricus CICC 6047 using pan-genomics analysis.Semantic proximity
Potential probiotic characteristics and genomic analysis of a new folate‐producing lactic acid bacteria <scp><i>Lactiplantibacillus plantarum</i> ZFM55</scp>Semantic proximity
Select a neighboring publication to make it the new centre.