Article

The stress-induced lincRNA <i>JUNI</i> is a critical factor for cancer cell survival whose interactome is a prognostic signature in clear cell renal cell carcinoma

2023-10-26

Abstract excerpt

Cancer cells rely on adaptive mechanisms to survive the multiple stressors they encounter, including replication stress, toxic metabolic products and exposure to genotoxic drugs. Understanding the factors involved in these stress responses is crucial for developing effective treatments. Here, we describe a previously unstudied long non-coding RNA (lncRNA), JUNI ( JUN-DT , LINC01135 ), which is regulated by MAPK...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4afb4076-f4ce-5a7a-b292-79d217cc588f
DOI: 10.1101/2023.10.23.563579

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 9 closest

The stress-induced lincRNA <i>JUNI</i> is a critical factor for cancer cell survival whose interactome is a prognostic signature in clear cell renal cell carcinomaDOI 10.1101/2023.10.23.563579Read

Investigation of the mechanisms underlying the regulation of macrophage activation and glomerular inflammation by JunDSemantic proximity Read

Aberrant expression of c-Jun in glioblastoma by internal ribosome entry site (IRES)-mediated translational activationSemantic proximity Read

Conserved architecture of a functional lncRNA-protein interaction in the DNA damage response pathwaySemantic proximity Read

Integrating single-cell RNA-seq and bulk RNA-seq reveals ischemic injury Promoting polyomavirus replication by DNA damage responseSemantic proximity Read

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)Semantic proximity Read

Jun, the oncoprotein.Semantic proximity Read

A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancerSemantic proximity Read

The effect of compound kushen injection on cancer cells: Integrated identification of candidate molecular mechanismsSemantic proximity Read

Hyperactivated JNK Is a Therapeutic Target in pVHL-Deficient Renal Cell CarcinomaSemantic proximity Read