Article

Integrating single-cell RNA-seq and bulk RNA-seq reveals ischemic injury Promoting polyomavirus replication by DNA damage response

2025-07-06

Abstract excerpt

Abstract: BK polyomavirus (BKPyV) can establish persistent infections in 90% of the healthy adult population, and its reactivation is associated with graft failure in kidney transplant patients. Ischemic injury (IS) increases the risk of viral reactivation, making BKPyV a primary cause of allograft failure. However, the detailed molecular mechanisms of IS that promote BKPyV replication are not well characterized....

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Literature Corpus work: 0350a23b-7f04-5f9d-995d-dcd9cd83289a
DOI: 10.22541/au.175182847.70629057/v1

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