Article
Oxidative stress alters transcript localization of disease-causing genes in the retinal pigment epithelium
2021-01-08
Abstract excerpt
Nuclear retention is a mechanism whereby RNA transcripts are held in the nucleus to maintain a proper nuclear-to-cytoplasmic balance or as a stockpile for use in responding to stimuli. Many mechanisms are employed to determine whether transcripts are retained or exported to the cytoplasm, though the extent to which tissue- or cell-type, stressors, or disease pathogenesis affect this process remains unclear. As the...
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Identifiers and source
- Literature Corpus work
- 4af9a632-a675-5f12-b07c-0509ef73344e
- DOI
- 10.1101/2021.01.07.425741