Influence of Epigenetic Regulators Expression on Gastric Cancer Prognosis

Abstract excerpt

Gastric cancer (GC) is the fourth leading cause of cancer-related death worldwide. High mortality is largely associated with late diagnosis and tumor heterogeneity, highlighting the need for molecular insights. Epigenetic alterations, including histone modifications and DNA/RNA methylation, play a key role in gene regulation, tumor progression, and therapy response. This study analyzed 179 samples (156 tumor, 23 n...

Topics

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• Chromatin Assembly and Disassembly
• DNA Methylation
• Gene Expression Regulation, Neoplastic
• Receptor Protein-Tyrosine Kinases
• rhoA GTP-Binding Protein
• Stem Cells
• Stomach Neoplasms
• Tumor Suppressor Protein p53

Identifiers and source

Literature Corpus work

4adba655-e200-5f0a-b9c4-f502e56342d1

DOI

10.1101/2025.09.12.25335661