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Therapeutic Potential of Arimoclomol Nanomicelles: In Vitro Impact on Alzheimer’s and Parkinson’s Pathology and Correlation with In Vivo Inflammatory Response

5 Feb 2025

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide This study investigates the potential of arimoclomol-loaded nanomicelles for the treatment of neurodegenerative diseases like Alzheimer’s and Parkinson’s, as well as their anti-inflammatory properties. Arimoclomol, a coinducer of heat shock proteins (HSPs), has shown clinical promise in mitigating protein misfolding, a hallmark of these diseases. In this work,...

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PMID: 39907698
DOI: 10.1021/acschemneuro.4c00734

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