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High Throughput Sequencing for Clinical Tuberculosis: An Overview

14 Nov 2022

Abstract excerpt

High throughput sequencing (HTS) can identify the presence of Mycobacterium tuberculosis DNA in a clinical sample while also providing information on drug susceptibility. Multiple studies have provided a context for exploring the clinical application of HTS for TB diagnosis. The workflow challenges, strengths and limitations of the various sequencing platforms, and tools used for analysis are presented to provide...

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PMID: 36422596
DOI: 10.3390/pathogens11111343

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