Article

Development and Use of Oral Microbiome Optimised Oxford Nanopore 16S Primers to Elucidate the Effect of Sialidase Inhibitors on a Plaque Community Biofilm Model

2025-11-26

Abstract excerpt

The oral microbiome is a diverse ecosystem that plays a critical role in health and disease and contains numerous bacterial species capable of metabolizing host-derived glycans, particularly sialic acids. Sialidase enzymes can be produced by both commensal and pathogenic bacteria, influencing biofilm formation and host-interactions. To investigate how sialidase activity might influence the oral microbiome we condu...

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Literature Corpus work: 4aaafee9-f0e9-5d19-986e-5d9198349efa
DOI: 10.1099/acmi.0.001143.v1

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