Article
Uncovering oral Neisseria tropism and persistence using metagenomic sequencing.
Nature microbiology - 27 May 2016
Donati Claudio, Zolfo Moreno, Albanese Davide, Tin Truong Duy, Asnicar Francesco, Iebba Valerio, Cavalieri Duccio, Jousson Olivier, De Filippo Carlotta, Huttenhower Curtis, Segata Nicola
Abstract excerpt
Microbial epidemiology and population genomics have previously been carried out near-exclusively for organisms grown in vitro. Metagenomics helps to overcome this limitation, but it is still challenging to achieve strain-level characterization of microorganisms from culture-independent data with sufficient resolution for epidemiological modelling. Here, we have developed multiple complementary approaches that can...
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