Article

Toll-like receptor 2 orchestrates a potent anti-tumor response in non-small cell lung cancer

2021-06-05

Abstract excerpt

Targeting early-stage lung cancer is vital to improve overall survival. We previously identified Toll-like receptor 2 (TLR2) as a regulator of oncogene-induced senescence (OIS) and the senescence-associated secretory phenotype (SASP), both key for tumor suppression. Here, we demonstrate that TLR2 is widely expressed in human lung tumor epithelium where it correlates with improved survival and clinical regression....

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Literature Corpus work: 4a96fa52-2fcb-53df-97e6-aeadf625b54d
DOI: 10.1101/2021.06.04.446876

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